MEF2A, myocyte enhancer factor 2A, 4205

N. diseases: 99; N. variants: 14
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Myocyte Enhancer Factor-2A Gene Mutation and Coronary Artery Disease. 26415812 2015
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Association of MEF2A gene 3'UTR mutations with coronary artery disease. 26400337 2015
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE MEF2A gene mutations and susceptibility to coronary artery disease in the Chinese population. 25366733 2014
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Variants in exon 11 of MEF2A gene and coronary artery disease: evidence from a case-control study, systematic review, and meta-analysis. 22363637 2012
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 Biomarker disease BEFREE A study of the role of the Myocyte-specific Enhancer Factor-2A gene in coronary artery disease. 19782985 2010
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE This finding raises the possibility that MEF2A variants may contribute to the risk of coronary artery disease. 19153100 2010
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Structural changes in exon 11 of MEF2A are not related to sporadic coronary artery disease in Han Chinese population. 20546016 2010
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 Biomarker disease BEFREE However, the association of MEF2A with coronary artery disease/MI was not confirmed in other studies. 20031581 2009
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease LHGDN Relationship of the CAG repeat polymorphism of the MEF2A gene and coronary artery disease in a Chinese population. 17579569 2007
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Relationship of the CAG repeat polymorphism of the MEF2A gene and coronary artery disease in a Chinese population. 17579569 2007
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Polymorphisms in myocyte enhancer factor 2A, a transcription factor, tumor necrosis factor (ligand) superfamily, member 4, the OX40 ligand, and proprotein convertase subtilisin/kexin type 9, which affect low-density lipoprotein levels, have all been associated with an altered risk of coronary artery disease and myocardial infarction. 16943719 2006
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 Biomarker disease BEFREE Positional cloning based on genome-wide linkage analysis with large families identified the first non - lipid-related disease-causing gene, MEF2A (encoding a transcriptional factor), for coronary artery disease and myocardiaI infarction. 15861005 2005
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Recently, a mutation in the human MEF2A gene was reported to be responsible for an autosomal dominant form of coronary artery disease, so the purpose of the present study was to assess the significance of MEF2A mutations in Japanese subjects with myocardial infarction (MI). 16195615 2005
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE MEF2A sequence variants and coronary artery disease: a change of heart? 15841171 2005
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE However, we did identify the 21-bp MEF2A coding sequence deletion originally implicated in adCAD1 in 1 of 300 elderly control subjects without CAD. 15841183 2005
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Transcription factor MEF2A mutations in patients with coronary artery disease. 15496429 2004
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Mutation of MEF2A in an inherited disorder with features of coronary artery disease. 14645853 2003