MEFV, MEFV innate immuity regulator, pyrin, 4210

N. diseases: 410; N. variants: 72
Disease: Autoimmune Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.040 Biomarker group BEFREE Genetic polymorphisms in genes coding for inflammasome components <i>nucleotide-binding oligomerization domain leucine rich repeat and pyrin domain-containing protein 3 (NLRP3)</i> and <i>caspase recruitment domain-containing protein 8 (CARD8)</i> have been associated with autoinflammatory and autoimmune diseases. 30915320 2019
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.040 Biomarker group BEFREE The discovery of these two bioactive compounds may help to further unveil the importance of pyrin in gut homeostasis and autoimmune diseases. 30647128 2019
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.040 GeneticVariation group BEFREE This is the second Th1-type autoimmune disease in which MEFV mutations have been shown to aggravate the clinical status. 15958759 2005
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.040 GeneticVariation group BEFREE In conclusion, the prevalence of definite immunorheumatological diseases and the absence of the mutations linked to FMF reinforce the notion that idiopathic acute recurrent pericarditis is an autoimmune condition. 16218464 2005