MEIS1, Meis homeobox 1, 4211

N. diseases: 104; N. variants: 19
Disease: Acute leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085669
Disease: Acute leukemia
Acute leukemia 		0.050 Biomarker disease BEFREE Deregulation of the HOXA9/MEIS1 axis in acute leukemia. 27258906 2016
CUI: C0085669
Disease: Acute leukemia
Acute leukemia 		0.050 AlteredExpression disease BEFREE In addition, we show that HOXA9 and MEIS1 overexpression are inversely correlated with relapse and overall survival, so the genes could become useful predictive markers of the clinical course of pediatric acute leukemias. 26059450 2015
CUI: C0085669
Disease: Acute leukemia
Acute leukemia 		0.050 AlteredExpression disease BEFREE Our results suggest that an intronic enhancer regulates the expression of MEIS1 in hematopoiesis and contributes to its aberrant expression in acute leukemia. 24022755 2014
CUI: C0085669
Disease: Acute leukemia
Acute leukemia 		0.050 AlteredExpression disease BEFREE Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation. 21518888 2011
CUI: C0085669
Disease: Acute leukemia
Acute leukemia 		0.050 AlteredExpression disease BEFREE Hoxa9 and Meis1 expression was correlated in hematopoietic progenitors and acute leukemias. 19620287 2009