Disease: Cerebral Infarction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction 		0.240 Biomarker disease BEFREE Many experimental studies have shown the association of apoptosis signal-regulating kinase 1 (ASK1) with cellular pathomechanisms after cerebral ischemia. 29743976 2018
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction 		0.240 Biomarker disease BEFREE The objective of the present study was to evaluate the role of ASK1 in controlling NLRP2 inflammasomes in astrocytes after cerebral ischemia. 30172704 2018
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction 		0.240 Biomarker disease BEFREE Herein, we focus on apoptosis signal-regulating kinase 1 (ASK1), which is involved in apoptotic cell death, brain infarction, and production of inflammatory mediators after cerebral ischemia. 28855861 2017
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction 		0.240 AlteredExpression disease BEFREE Here we reported ASK1 was activated by nitric oxide (NO) through S-nitrosylation during cerebral ischemia-reperfusion. 23137546 2013
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction 		0.240 Therapeutic disease RGD As a result of RNAi, corresponding mRNA was distinctly degraded, expression of Ask1 protein was obviously suppressed, apoptotic cell death was apparently decreased and cerebral infarct area was significantly reduced. 23968852 2013