Disease: Diabetes Mellitus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.340 Biomarker group BEFREE This ASK1 activation strongly correlated with islet amyloidosis and diabetes progression. 29627323 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.340 GeneticVariation group BEFREE These findings suggest that ER stress-induced ASK1-p38 activation, which is triggered by the accumulation of Ins(C96Y), plays an important role in the pathogenesis of diabetes. 23416061 2013
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.340 AlteredExpression group BEFREE Diabetes was associated with higher OM Ask1-mRNA only in the lean group. 19351724 2009
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.340 Biomarker group BEFREE Thioredoxin and binding proteins (ASK1 and TBP2) appear to control apoptosis or metabolic states such as carbohydrate and lipid metabolism related to diseases such as diabetes and atherosclerosis. 17115886 2007
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.340 Biomarker group CTD_human Apoptosis signal-regulating kinase 1 mediates cellular senescence induced by high glucose in endothelial cells. 16731828 2006