|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Macrophage Migration Inhibitory Factor Promotes the Interaction between the Tumor, Macrophages, and T Cells to Regulate the Progression of Chemically Induced Colitis-Associated Colorectal Cancer.
|
31360118 |
2019 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
In addition, an increase in expression of the macrophage-migration inhibitory factor was observed at the tumor margin in mice inoculated with CD133<sup>+</sup> LNCaP cells.
|
31423179 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Macrophage migration inhibitory factor promotes tumor aggressiveness of esophageal squamous cell carcinoma via activation of Akt and inactivation of GSK3β.
|
29079416 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The disease-related structural isoform of MIF (oxMIF) can be specifically and predominantly detected in the circulation of patients with inflammatory diseases and in tumor tissue, whereas the ubiquitously expressed isoform of MIF (redMIF) is abundantly expressed in healthy and diseased subjects.
|
29412660 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Loss of keratinocyte-derived MIF leads to a loss of control of epithelial skin tumor formation in chemical skin carcinogenesis, which highlights an unexpected tumor-suppressive activity of MIF in murine skin.-Brocks, T., Fedorchenko, O., Schliermann, N., Stein, A., Moll, U. M., Seegobin, S., Dewor, M., Hallek, M., Marquardt, Y., Fietkau, K., Heise, R., Huth, S., Pfister, H., Bernhagen, J., Bucala, R., Baron, J. M., Fingerle-Rowson, G. Macrophage migration inhibitory factor protects from nonmelanoma epidermal tumors by regulating the number of antigen-presenting cells in skin.
|
27825106 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Twenty diagnostic protein signals were found characteristic for specific tumors (p ≤ 0.05), amongst them acyl-CoA-binding protein (m/z 11 162), macrophage migration inhibitory factor (m/z 12 350), thioredoxin (m/z 11 608) and galectin-1 (m/z 14 633) were assigned.
|
27174013 |
2016 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
We then generate cross-species expression networks to recapitulate a known association between tumor epithelial cells and fibroblast activation, and propose a potentially novel relationship between two hypoxia-associated genes, human MIF and mouse Ddx6.
|
26980748 |
2016 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Importantly, we show that knockdown of either CXCR4 or MIF abrogates MSC homing to tumors in an in vivo pulmonary metastasis model, confirming the in vitro two-dimensional and three-dimensional assays.
|
25712213 |
2015 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma.
|
22821831 |
2013 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Together with histological grade, increased co-expression of MIF and MMP9 in tumor might be a valuable predictor for recurrence, especially for benign meningiomas.
|
23372434 |
2013 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Macrophage migration inhibitory factor produced by the tumour stroma but not by tumour cells regulates angiogenesis in the B16-F10 melanoma model.
|
22955855 |
2012 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
MIF can promote tumor cell survival, and elevated MIF protein correlates with tumor aggressiveness and poor prognosis.
|
22271573 |
2012 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Our study adds another puzzle stone to the role of MIF in tumor growth and progression by showing the importance of MIF for overcoming contact inhibition.
|
20038293 |
2009 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Tumor growth-promoting properties of macrophage migration inhibitory factor.
|
19128232 |
2008 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Amplification of tumor hypoxic responses by macrophage migration inhibitory factor-dependent hypoxia-inducible factor stabilization.
|
17210698 |
2007 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
We conclude that TNF-alpha, via NF-kappaB, and JNK induces MIF and EMMPRIN in macrophage to tumor cell cocultures and this leads to increased invasive capacity of the tumor cells.
|
16002723 |
2005 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
MIF protein expression significantly correlated with the grade of tumor differentiation.
|
15064733 |
2004 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Suppression of tumor growth through introduction of an antisense plasmid of macrophage migration inhibitory factor.
|
12373295 |
2002 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
High expression of macrophage migration inhibitory factor in human melanoma cells and its role in tumor cell growth and angiogenesis.
|
10544003 |
1999 |