CXCL9, C-X-C motif chemokine ligand 9, 4283

N. diseases: 269; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.340 GeneticVariation disease BEFREE Formalin-fixed paraffin-embedded tissue blocks from patients with intermediate/high-risk, early breast cancer, treated with sequential adjuvant epirubicin, paclitaxel, and cyclophosphamide methotrexate fluorouracil within a randomized trial, were tested for CXCL13 and CXCL9 messenger RNA expression; 557 patients with adequate tissue were eligible for the analysis. 31699671 2020
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.340 AlteredExpression disease BEFREE Significantly, high transcription levels of CXCL9/12/13/14 conferred an overall survival (OS) advantage in BC patients, while high levels of CXCL8 demonstrated shorter OS in all BC sufferers. 29495008 2018
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.340 AlteredExpression disease BEFREE CXCL9 was visualized in breast cancer specimens by immunohistochemistry, expression levels of CXCL9 and cyclooxygenases were determined by ELISA and western blotting, respectively. 22333315 2012
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.340 AlteredExpression disease BEFREE We identified two proteins (Fibronectin 1 and CXCL9) from a gene expression data set that included 120 BC samples and 45 benign lesions. 20068563 2010
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.340 Biomarker disease CTD_human Quantitative RT-PCR demonstrated that six genes from the combined signatures (CXCL9, ITSN2, GNAI2, H2AFX, INDO, and MGC10986) were significantly differentially expressed in the recurrence versus the non-recurrence group of the 19 cases and the independent breast cancer patient cohort (n = 51) treated with CMF. 18925433 2009
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.330 GeneticVariation disease BEFREE Formalin-fixed paraffin-embedded tissue blocks from patients with intermediate/high-risk, early breast cancer, treated with sequential adjuvant epirubicin, paclitaxel, and cyclophosphamide methotrexate fluorouracil within a randomized trial, were tested for CXCL13 and CXCL9 messenger RNA expression; 557 patients with adequate tissue were eligible for the analysis. 31699671 2020
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.330 AlteredExpression disease BEFREE CXCL9 was visualized in breast cancer specimens by immunohistochemistry, expression levels of CXCL9 and cyclooxygenases were determined by ELISA and western blotting, respectively. 22333315 2012
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.330 AlteredExpression disease BEFREE We identified two proteins (Fibronectin 1 and CXCL9) from a gene expression data set that included 120 BC samples and 45 benign lesions. 20068563 2010
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.330 Biomarker disease CTD_human Quantitative RT-PCR demonstrated that six genes from the combined signatures (CXCL9, ITSN2, GNAI2, H2AFX, INDO, and MGC10986) were significantly differentially expressed in the recurrence versus the non-recurrence group of the 19 cases and the independent breast cancer patient cohort (n = 51) treated with CMF. 18925433 2009
CUI: C0014175
Disease: Endometriosis
Endometriosis 		0.310 Biomarker disease CTD_human Elevated serum chemokines are independently associated with both endometriosis and uranium exposure. 30579999 2019
CUI: C0014175
Disease: Endometriosis
Endometriosis 		0.310 AlteredExpression disease BEFREE Serum levels of AXIN1 and ST1A1 were increased in endometriosis compared with MC (<i>p</i> < 0.001) and healthy controls (<i>p</i> = 0.001), whereas CXCL9 levels were decreased. 30621017 2019
CUI: C0032300
Disease: Lobar Pneumonia
Lobar Pneumonia 		0.310 Biomarker disease BEFREE However, upon induction of pneumococcal pneumonia in aged mice, delayed production of certain analytes, such as IFN-γ, MIG (CXCL9), IP-10 (CXCL10), MCP-1 (CCL2), TARC (CCL17) and MDC (CCL22) became apparent. 30463053 2018
CUI: C0032300
Disease: Lobar Pneumonia
Lobar Pneumonia 		0.310 Biomarker disease CTD_human Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression. 21625544 2011
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis 		0.310 Biomarker disease CTD_human Gene expression profiling of early primary biliary cirrhosis: possible insights into the mechanism of action of ursodeoxycholic acid. 18422935 2008
CUI: C0023892
Disease: Biliary cirrhosis
Biliary cirrhosis 		0.310 Biomarker disease CTD_human Gene expression profiling of early primary biliary cirrhosis: possible insights into the mechanism of action of ursodeoxycholic acid. 18422935 2008
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis 		0.310 AlteredExpression disease BEFREE By immunohistochemistry, IP-10 and MIG expressions were evident in the portal areas in PBC. 16243485 2005
CUI: C0023892
Disease: Biliary cirrhosis
Biliary cirrhosis 		0.310 AlteredExpression disease LHGDN Increased levels of chemokine receptor CXCR3 and chemokines IP-10 and MIG in patients with primary biliary cirrhosis and their first degree relatives. 16243485 2005
CUI: C0269102
Disease: Endometrioma
Endometrioma 		0.300 Biomarker disease CTD_human Elevated serum chemokines are independently associated with both endometriosis and uranium exposure. 30579999 2019
CUI: C0007570
Disease: Celiac Disease
Celiac Disease 		0.300 Biomarker disease CTD_human Celiac disease biomarkers identified by transcriptome analysis of small intestinal biopsies. 30097691 2018
CUI: C0007282
Disease: Carotid Stenosis
Carotid Stenosis 		0.300 Biomarker disease CTD_human Elevated levels of endothelial-derived microparticles, and serum CXCL9 and SCGF-β are associated with unstable asymptomatic carotid plaques. 26564003 2015
CUI: C0340569
Disease: Internal Carotid Artery Stenosis
Internal Carotid Artery Stenosis 		0.300 Biomarker disease CTD_human Elevated levels of endothelial-derived microparticles, and serum CXCL9 and SCGF-β are associated with unstable asymptomatic carotid plaques. 26564003 2015
CUI: C0751633
Disease: Carotid Artery Plaque
Carotid Artery Plaque 		0.300 Biomarker disease CTD_human Elevated levels of endothelial-derived microparticles, and serum CXCL9 and SCGF-β are associated with unstable asymptomatic carotid plaques. 26564003 2015
CUI: C0751634
Disease: Carotid Ulcer
Carotid Ulcer 		0.300 Biomarker phenotype CTD_human Elevated levels of endothelial-derived microparticles, and serum CXCL9 and SCGF-β are associated with unstable asymptomatic carotid plaques. 26564003 2015
CUI: C0751635
Disease: Common Carotid Artery Stenosis
Common Carotid Artery Stenosis 		0.300 Biomarker disease CTD_human Elevated levels of endothelial-derived microparticles, and serum CXCL9 and SCGF-β are associated with unstable asymptomatic carotid plaques. 26564003 2015
CUI: C0751636
Disease: External Carotid Artery Stenosis
External Carotid Artery Stenosis 		0.300 Biomarker disease CTD_human Elevated levels of endothelial-derived microparticles, and serum CXCL9 and SCGF-β are associated with unstable asymptomatic carotid plaques. 26564003 2015