ATXN3, ataxin 3, 4287

N. diseases: 207; N. variants: 12
Disease: Narcolepsy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027404
Disease: Narcolepsy
Narcolepsy 		0.030 Biomarker disease BEFREE In both the orexin knockout and the orexin-ataxin-3 mouse models of narcolepsy we have found that cataplexy can be blocked if the surrogate neurons are part of the circuit responsible for cataplexy. 28445807 2017
CUI: C0027404
Disease: Narcolepsy
Narcolepsy 		0.030 Biomarker disease BEFREE These findings indicate that the orexin/ataxin-3 transgenic rat could provide a useful model of human narcolepsy. 15128861 2004
CUI: C0027404
Disease: Narcolepsy
Narcolepsy 		0.030 Biomarker disease BEFREE Orexin/ataxin-3 mice provide a valuable model for studying the pathophysiology and treatment of narcolepsy. 11394998 2001