ATXN3, ataxin 3, 4287

N. diseases: 207; N. variants: 12
Disease: Depressed mood ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.030 Biomarker phenotype BEFREE Fatigue is frequent and strongly associated with depression and excessive daytime somnolence in SCA3/MJD. 27021342 2017
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.030 GeneticVariation phenotype BEFREE We concluded that: decision-making regarding presymptomatic testing seems to be genuinely autonomous, since after genetic counseling half the individuals who asked for presymptomatic testing decided in favor and half decided against it; general characteristics of Brazilians who sought presymptomatic testing were similar to many European samples studied previously; and individuals at risk for SCA3 may be at greater risk of depression. 21717286 2012
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.030 Biomarker phenotype BEFREE Fully established MJD in this family seemed to exert a protective effect from depression. 8215926 1993