MLF1, myeloid leukemia factor 1, 4291

N. diseases: 37; N. variants: 1
Disease: Lymphopenia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024312
Disease: Lymphopenia
Lymphopenia 		0.010 GeneticVariation disease BEFREE Importantly, Mlf1 deletion reverses B- and T-cell lymphopenia and significantly ameliorates the progressive striatal and cerebellar neurodegeneration observed in Hax1<sup>-/-</sup> mice, with a doubling of the lifespan of Mlf1<sup>-/-</sup>/Hax1<sup>-/-</sup> animals compared to Hax1<sup>-/-</sup> animals. 28137643 2017