MLH1, mutL homolog 1, 4292

N. diseases: 526; N. variants: 757
Disease: Adult Diffuse Large Cell Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278762
Disease: Adult Diffuse Large Cell Lymphoma
Adult Diffuse Large Cell Lymphoma 		0.010 GeneticVariation disease BEFREE To determine the type and pattern of genomic instability occurring in histological transformation of FCLs and the role of DNA mismatch repair defects in this procedure, we have performed microsatellite analysis, comparative genomic hybridization (CGH) and mutational analysis of hMLH1 and hMSH2 genes on serial biopsy specimens from patients with FCL transformed to diffuse large cell lymphoma (DLCL). 11187904 2000