MLH1, mutL homolog 1, 4292

N. diseases: 31; N. variants: 711
Disease: Breast Cancer, Familial ×
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.320 Biomarker disease CLINGEN Associations Between Cancer Predisposition Testing Panel Genes and Breast Cancer. 28418444 2017
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.320 Biomarker disease CLINGEN Lynch syndrome caused by MLH1 mutations is associated with an increased risk of breast cancer: a cohort study. 26101330 2015
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.320 Biomarker disease CLINGEN Risks of less common cancers in proven mutation carriers with lynch syndrome. 23091106 2012
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.320 Biomarker disease CLINGEN Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study. 22331944 2012
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.320 Biomarker disease CLINGEN The extracolonic cancer spectrum in females with the common 'South African' hMLH1 c.C1528T mutation. 18049911 2008
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.320 Biomarker disease CLINGEN Hereditary nonpolyposis colorectal cancer in 95 families: differences and similarities between mutation-positive and mutation-negative kindreds. 11112663 2001