KMT2A, lysine methyltransferase 2A, 4297

N. diseases: 535; N. variants: 65
Disease: Acute monoblastic leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0457334
Disease: Acute monoblastic leukemia
Acute monoblastic leukemia 		0.100 AlteredExpression disease BEFREE Segmental amplification of MLL gene associated with high expression of AURKA and AURKB genes in a case of acute monoblastic leukemia with complex karyotype. 20303016 2010
CUI: C0457334
Disease: Acute monoblastic leukemia
Acute monoblastic leukemia 		0.100 Biomarker disease BEFREE A novel AF9 breakpoint in MLL-AF9-positive acute monoblastic leukemia. 18000862 2008
CUI: C0457334
Disease: Acute monoblastic leukemia
Acute monoblastic leukemia 		0.100 GeneticVariation disease BEFREE Rearrangement of MLL in a patient with congenital acute monoblastic leukemia and granulocytic sarcoma associated with a t(1;11)(p36;q23) translocation. 15621793 2005
CUI: C0457334
Disease: Acute monoblastic leukemia
Acute monoblastic leukemia 		0.100 Biomarker disease BEFREE MLL-MLLT10 fusion in acute monoblastic leukemia: variant complex rearrangements and 11q proximal breakpoint heterogeneity. 15262427 2004
CUI: C0457334
Disease: Acute monoblastic leukemia
Acute monoblastic leukemia 		0.100 Biomarker disease BEFREE MLLT10 (previously called AF10) is a moderately common MLL fusion partner predominantly occurring in acute monoblastic leukemia (AML-M5). 11896537 2002
CUI: C0457334
Disease: Acute monoblastic leukemia
Acute monoblastic leukemia 		0.100 GeneticVariation disease BEFREE We analyzed one patient with de novo acute monoblastic leukemia with t(11;14)(q23;q24) and identified that a human homologue of gephyrin (human gephyrin) fused with MLL. 11289145 2001
CUI: C0457334
Disease: Acute monoblastic leukemia
Acute monoblastic leukemia 		0.100 GeneticVariation disease BEFREE FISH analysis of an AML-M5a with segmental rearrangements involving 11q23-MLL region. 10731590 2000
CUI: C0457334
Disease: Acute monoblastic leukemia
Acute monoblastic leukemia 		0.100 GeneticVariation disease BEFREE Progression from myelodysplastic syndrome with monosomy 7 to acute monoblastic leukemia with MLL gene rearrangement. 9594441 1998
CUI: C0457334
Disease: Acute monoblastic leukemia
Acute monoblastic leukemia 		0.100 GeneticVariation disease BEFREE Translocation (10;11)(p13;q13) and MLL gene rearrangement in a case of AML (M5a) with aggressive leukemia cutis. 9648554 1998
CUI: C0457334
Disease: Acute monoblastic leukemia
Acute monoblastic leukemia 		0.100 GeneticVariation disease BEFREE Two acute monocytic leukemia (AML-M5a) cell lines (MOLM-13 and MOLM-14) with interclonal phenotypic heterogeneity showing MLL-AF9 fusion resulting from an occult chromosome insertion, ins(11;9)(q23;p22p23). 9305600 1997
CUI: C0457334
Disease: Acute monoblastic leukemia
Acute monoblastic leukemia 		0.100 AlteredExpression disease BEFREE In the case of AML M5a with t(11;19), the tumour cells with ALL-1 rearrangement expressed CD34. 8616034 1996