Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036690
Disease: Septicemia
Septicemia
0.040 Biomarker disease BEFREE Since polymorphonuclear neutrophils (PMNs) play a pivotal role in the early phase of sepsis, we evaluated the potential therapeutic effects of cholinesterase inhibitors on PMN functions during cecal ligation and puncture- (CLP-) induced sepsis and investigated the roles of AChE and BChE as inflammatory markers under standardized experimental conditions. 30804708 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.040 AlteredExpression disease BEFREE Experimental sepsis induces sustained inflammation and acetylcholinesterase activity impairment in the hypothalamus. 30190086 2018
CUI: C0036690
Disease: Septicemia
Septicemia
0.040 AlteredExpression disease BEFREE In this study, we aimed to investigate whether the decreased AChE activity was related to oxidative stress by observing AChE activity in different grades of sepsis induced by caecal ligation and puncture (CLP). 29230271 2017
CUI: C0036690
Disease: Septicemia
Septicemia
0.040 AlteredExpression disease BEFREE Furthermore, the present study aimed to elucidate the association between AChE activity and its expression at the NMJ during sepsis. 28849127 2017