MMP1, matrix metallopeptidase 1, 4312

N. diseases: 589; N. variants: 19
Disease: airway disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699949
Disease: airway disease
airway disease 		0.020 AlteredExpression disease BEFREE Exposure or colonization by SA in the airway may enhance the remodeling of tissue through a TGF-α-dependent induction of MMP-1 expression, and may thereby promote remodeling in airway diseases in which SA is implicated, such as asthma and chronic rhinosinusitis. 25180535 2015
CUI: C0699949
Disease: airway disease
airway disease 		0.020 Biomarker disease BEFREE We also found that the chronic obstructive pulmonary disease (COPD)-predisposing TRPV4P19S variant enhances Ca2+ influx and MMP 1 activation, providing mechanistic linkage between man-made air pollution and human airway disease. 21245013 2011