MMP2, matrix metallopeptidase 2, 4313

N. diseases: 1021; N. variants: 43
Disease: Aortic Rupture ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003496
Disease: Aortic Rupture
Aortic Rupture 		0.310 Biomarker disease BEFREE Intriguingly, despite early up-regulation of MMP2 in Timp3(-/-)Ang II aortas, additional deletion of Mmp2 in these mice (Timp3(-/-)/Mmp2(-/-)) resulted in exacerbated AAA, compromised survival due to aortic rupture, and inflammation in the abdominal aorta. 23144462 2012
CUI: C0003496
Disease: Aortic Rupture
Aortic Rupture 		0.310 Biomarker disease CTD_human Doxycycline delays aneurysm rupture in a mouse model of Marfan syndrome. 18178469 2008