MMP2, matrix metallopeptidase 2, 4313

N. diseases: 1021; N. variants: 43
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0162810
Disease: Cicatrix, Hypertrophic
Cicatrix, Hypertrophic
0.030 AlteredExpression disease BEFREE There was a significant upregulation of the mRNA expression of matrix metalloproteinase-2 (MMP2) and MMP9 in primary HS fibroblasts in response to mechanical stress. 25166894 2015
CUI: C0162810
Disease: Cicatrix, Hypertrophic
Cicatrix, Hypertrophic
0.030 AlteredExpression disease BEFREE Western blotting assays further revealed that Mmp9 and Mmp12 expression increased significantly in the hypertrophic scar tissue after pressure therapy (P < 0.05) but not Mmp2 expression (P > 0.05). 24033957 2013
CUI: C0162810
Disease: Cicatrix, Hypertrophic
Cicatrix, Hypertrophic
0.030 AlteredExpression disease BEFREE The relative expression of MMP 2 was significantly higher in samples of proliferative hypertrophic scars after burn injury. 19464975 2010