MMP2, matrix metallopeptidase 2, 4313

N. diseases: 1021; N. variants: 43
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278877
Disease: Adult Meningioma
Adult Meningioma
0.030 Biomarker disease BEFREE Results indicated very high gene expression of 13 proteases, inhibitors and growth factors studied: MMP2 and MMP14, TIMP-1, -2 and -3, ADAM9, 10, 12, 15 and 17, EGF-R, EMMPRIN and VEGF-A, in almost every meningioma. 27779709 2016
CUI: C0278877
Disease: Adult Meningioma
Adult Meningioma
0.030 GeneticVariation disease BEFREE In future studies, these gene polymorphisms, especially MMP2 1306C>T and 1575G>A, should be investigated for meningioma or brain invasion susceptibility in larger study groups. 25259564 2014
CUI: C0278877
Disease: Adult Meningioma
Adult Meningioma
0.030 AlteredExpression disease BEFREE Expression of MMP-2 and -9 in short-term cultures of meningioma: influence of histological subtype. 14612977 2003