MMP3, matrix metallopeptidase 3, 4314

N. diseases: 473; N. variants: 24
Disease: Glioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma 		0.040 AlteredExpression disease BEFREE Single-dose treatment with Dex did not significantly change glioma volume in nude mice, but changed the expression of Ki67 and matrix metalloproteinase-3 in the tumour. 31452248 2020
CUI: C0017638
Disease: Glioma
Glioma 		0.040 Biomarker disease BEFREE However, whether MMP-3 participates in the regulation of metastasis and its mechanisms in glioma is mostly unknown. 25252846 2014
CUI: C0017638
Disease: Glioma
Glioma 		0.040 AlteredExpression disease BEFREE Blockade of EGFR signaling promotes glioma stem-like cell invasiveness by abolishing ID3-mediated inhibition of p27(KIP1) and MMP3 expression. 23022473 2013
CUI: C0017638
Disease: Glioma
Glioma 		0.040 GeneticVariation disease BEFREE In summary, our results suggest that any one of MMP3 variants may not have a substantial effect on glioma risk, but a joint effect of MMP3 promoter polymorphisms may contribute to risk of gliomas, particularly for adult gliomas. 21853476 2012