MMP14, matrix metallopeptidase 14, 4323

N. diseases: 340; N. variants: 7
Disease: Osteitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029400
Disease: Osteitis
Osteitis 		0.010 Biomarker disease BEFREE These data provide the first genetic evidence that cells other than osteoclasts can cause focal bone destruction in inflammatory bone disease and suggest that MMP14 is a key mediator conferring pathological bone-resorbing capacity on c-Fos-deficient Sh3bp2<sup>KI/KI</sup> macrophages. 28914985 2018