Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0008626
Disease: Congenital chromosomal disease
Congenital chromosomal disease
0.010 GeneticVariation group BEFREE Structural alterations of the c-mos locus in benign pleomorphic adenomas with chromosome abnormalities of 8q12. 1677749 1991
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.010 GeneticVariation group BEFREE The frequency of the rare 5 kb c-mos allele was significantly higher than that observed in control groups of patients with colorectal neoplasms or lymphoproliferative disorders. 1679639 1991
CUI: C0011991
Disease: Diarrhea
Diarrhea
0.010 GeneticVariation phenotype BEFREE We observed a significant improvement in visual analogic scales at six month for dysmenorrhea (-3.6, p=0.004), dyspareunia (-2.4, p=0.006), diarrhea (-3.0, p=0.006), constipation (-3, p=0.002), dyschezia (-3.2, p=0.003), false urges to defecate (-3.3, p=0.007), posterior pelvic pain (-3.8, p=0.002), and asthenia (-4.3, p=0.002).There was also a significant improvement of the MOS-SF36 with an increase of both Physical Composite Score (+9.3%, p=0.002) and Mental Composite Score (+10.9%, p=0.017) at six months. 31788875 2019
CUI: C0013080
Disease: Down Syndrome
Down Syndrome
0.010 GeneticVariation disease BEFREE Translocation of the MOS gene in a rare t(8;16) associated with acute myeloblastic leukemia and Down syndrome. 2522812 1989
CUI: C0013390
Disease: Dysmenorrhea
Dysmenorrhea
0.010 GeneticVariation phenotype BEFREE We observed a significant improvement in visual analogic scales at six month for dysmenorrhea (-3.6, p=0.004), dyspareunia (-2.4, p=0.006), diarrhea (-3.0, p=0.006), constipation (-3, p=0.002), dyschezia (-3.2, p=0.003), false urges to defecate (-3.3, p=0.007), posterior pelvic pain (-3.8, p=0.002), and asthenia (-4.3, p=0.002).There was also a significant improvement of the MOS-SF36 with an increase of both Physical Composite Score (+9.3%, p=0.002) and Mental Composite Score (+10.9%, p=0.017) at six months. 31788875 2019
CUI: C0013473
Disease: Eating Disorders
Eating Disorders
0.010 GeneticVariation group BEFREE Participants completed a battery of established self-report measures assessing food addiction, binge-eating and eating-disorder psychopathology (Eating Disorder Examination-Questionnaire; EDE-Q), depressive symptoms (Patient Health Questionnaire-2; PHQ-2), and mental and physical functioning (MOS Short Form Health Survey; SF-12). 29870970 2018
CUI: C0016053
Disease: Fibromyalgia
Fibromyalgia
0.010 GeneticVariation disease BEFREE The scores in all sleep dimensions of the MOS-sleep were higher in CPP (more disturbances) compared to pain free patients, and differences were observed among the three groups of PCP, with FM most severely affected. 28945136 2018
CUI: C0022104
Disease: Irritable Bowel Syndrome
Irritable Bowel Syndrome
0.010 GeneticVariation disease BEFREE The secondary outcome measures will include the MOS 36-item short-form health survey (SF-36), IBS Quality of Life Questionnaire (IBS-QOL), severity of IBS symptoms (IBS-SSS), and rectal perception. 30572430 2018
CUI: C0023470
Disease: Myeloid Leukemia
Myeloid Leukemia
0.010 GeneticVariation disease BEFREE Identification in several human myeloid leukemias or cell lines of a DNA rearrangement next to the c-mos 3'-end. 2993032 1985
CUI: C0023895
Disease: Liver diseases
Liver diseases
0.010 GeneticVariation group BEFREE All patients and controls completed one generic HRQL questionnaire (MOS SF-36) and one liver-disease specific instrument (Chronic Liver Disease Questionnaire, CLDQ). 17406828 2007
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.010 GeneticVariation group BEFREE The frequency of the rare 5 kb c-mos allele was significantly higher than that observed in control groups of patients with colorectal neoplasms or lymphoproliferative disorders. 1679639 1991
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.010 GeneticVariation disease BEFREE Furthermore, knee function will be measured using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scale, and the quality of life will be measured using the MOS Item Short-form Health Survey (SF-36). 29764409 2018
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
0.010 GeneticVariation disease BEFREE Mutation analysis of the c-mos proto-oncogene and the endothelin-B receptor gene in medullary thyroid carcinoma and phaeochromocytoma. 8695346 1996
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms
0.010 GeneticVariation phenotype BEFREE Participants completed a battery of established self-report measures assessing food addiction, binge-eating and eating-disorder psychopathology (Eating Disorder Examination-Questionnaire; EDE-Q), depressive symptoms (Patient Health Questionnaire-2; PHQ-2), and mental and physical functioning (MOS Short Form Health Survey; SF-12). 29870970 2018
CUI: C0280131
Disease: Ovarian Teratoma
Ovarian Teratoma
0.010 GeneticVariation disease BEFREE We have analysed the entire coding region of the c-MOS gene in a series of human ovarian teratomas to determine whether there are any cancer-causing alterations. 9635841 1998
CUI: C0432306
Disease: Ichthyosis Bullosa of Siemens
Ichthyosis Bullosa of Siemens
0.010 GeneticVariation disease BEFREE The secondary outcome measures will include the MOS 36-item short-form health survey (SF-36), IBS Quality of Life Questionnaire (IBS-QOL), severity of IBS symptoms (IBS-SSS), and rectal perception. 30572430 2018
CUI: C1527390
Disease: Neoplasms, Intracranial
Neoplasms, Intracranial
0.010 GeneticVariation group BEFREE Rare Ha-ras and c-mos alleles in patients with intracranial tumors. 3352917 1988
CUI: C4521042
Disease: Complete Trisomy 21 Syndrome
Complete Trisomy 21 Syndrome
0.010 GeneticVariation disease BEFREE Translocation of the MOS gene in a rare t(8;16) associated with acute myeloblastic leukemia and Down syndrome. 2522812 1989
CUI: C4551683
Disease: Adrenal Gland Pheochromocytoma
Adrenal Gland Pheochromocytoma
0.010 GeneticVariation disease BEFREE Mutation analysis of the c-mos proto-oncogene and the endothelin-B receptor gene in medullary thyroid carcinoma and phaeochromocytoma. 8695346 1996
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.090 Biomarker group BEFREE Although this result is currently a matter of controversy, further studies must be independently repeated to be conclusive; -- another RFLP was found in c-mos proto-oncogene, which is detected only in patients with breast cancers or other types of tumors. 2905174 1988
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.090 Biomarker group BEFREE There was up to 5-fold enrichment of the targeted MSV in the bone marrow of mice bearing early or late stage MDA-MB-231 tumors and of mice with late stage, but not early stage, MCF-7 tumors. 24818768 2014
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.090 Biomarker group BEFREE How this process occurs and more importantly, why, has recently become the focus of several research groups, prompting this review in which we discuss two related phenomena that accompany the reversible polyploidy of tumor cells: the induction of meiosis genes such as MOS and the decrease in genomic instability observed during the reversion from polyploidy to para-diploidy. 20676137 2010
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.090 Biomarker group BEFREE Female transgenic mice lacking a functional c-mos proto-oncogene develop ovarian teratomas, indicating that c-mos may behave as a tumour-suppressor gene for this type of tumour. 9635841 1998
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.090 Biomarker group BEFREE In the present report, we examine, in a series of non-small cell lung carcinomas (NSCLCs), the status of K-ras and c-mos oncoproteins in correlation with the tumor neo-angiogenesis state and the major angiogenic factor, vascular endothelial growth factor (VEGF). 11778648 2001
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.090 Biomarker group BEFREE Rhim et al. were first to show that superinfection of Ad12-SV40-infected immortalized human epidermal cells with an RNA tumor virus containing a ras oncogene, such as Ki-MSV, or their treatment with chemical carcinogens, leads to the ability of cells to both grow in anchorage-independent fashion and to form tumors in athymic nude mice. 8330279 1993