MPO, myeloperoxidase, 4353

N. diseases: 653; N. variants: 25
Disease: Impaired cognition ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.030 AlteredExpression disease BEFREE This included prevention of cognitive impairment, alterations in the plasma levels of homocysteine and nitrate and the activity of acetylcholinesterase and myeloperoxidase and the tissue level of glutathione, and thiobarbituric acid reactive substances in the brain tissues. 31585870 2020
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.030 AlteredExpression disease BEFREE STZ injection and aging resulted in significant development of cognitive deficits; along-with enhancement of Myeloperoxidase (MPO) levels, Thiobarbituric Acid Reactive Species (TBARS), Acetylcholinestrase (AChE) activity, and reduced Glutathione (GSH) levels. 30101704 2018
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.030 Biomarker disease BEFREE In this sample, MPO AA, associated with decreased production of myeloperoxidase, was found to be a risk factor for cognitive decline. 16641309 2006