MPO, myeloperoxidase, 4353
N. diseases: 653; N. variants: 25
Source: ALL
| Disease | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year |
|---|---|---|---|---|---|---|---|
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0.050 | Biomarker | disease | BEFREE | Elimination of malignant cells through HOCl signaling is prevented by Helicobacter pylori-associated catalase and superoxide dismutase, whereas it is enhanced by low dose irradiation and by H<sub>2</sub>O<sub>2</sub>-producing lactobacilli in the presence of myeloperoxidase. | 29156213 | 2018 |
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0.050 | Biomarker | disease | BEFREE | Anti-secretory, mucus, K<sup>+</sup>-ATP channels, prostaglandins (PGs), nitric oxide (NO), TNF-α, IL-1β, IL-10, catalase (CAT) and myeloperoxidase (MPO) activities and in vitro Helicobacter pylori action by EOGi were evaluated. | 28763752 | 2017 |
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0.050 | GeneticVariation | disease | BEFREE | To elucidate the relations between the myeloperoxidase (-468)G-->A polymorphism and the development of duodenal ulcer (DU), and to investigate the impacts of this host genetic polymorphism on the histopathological features of Helicobacter pylori (H pylori)-related gastritis. | 15884126 | 2005 |
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0.050 | GeneticVariation | disease | BEFREE | The present study was conducted to re-examine the reported association between the myeloperoxidase (MPO) G-463A polymorphism and HP seropositivity in different subjects and to investigate interactions with smoking behavior and the interleukin-1B (IL-1B) C-31T polymorphism. | 12810834 | 2003 |
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0.050 | GeneticVariation | disease | BEFREE | Association of the myeloperoxidase -463G-->A polymorphism with development of atrophy in Helicobacter pylori-infected gastritis. | 12135010 | 2002 |