Depressive disorder
|
0.330 |
Biomarker
|
disease |
BEFREE |
Benefits of Physical Activity for Depression and Fatigue in Multiple Sclerosis: A Longitudinal Analysis.
|
30878208 |
2019 |
Depressive disorder
|
0.330 |
GeneticVariation
|
disease |
BEFREE |
Depression, fatigue and disability are independently associated with quality of life in patients with multiple Sclerosis: Results of a cross-sectional study.
|
31437741 |
2019 |
Depressive disorder
|
0.330 |
GeneticVariation
|
disease |
BEFREE |
A large two-centre survey included the MS Neuropsychological Screening Questionnaire (MSNQ), the two-question screening tool for depression, vitality, health-related quality of life, the Health-Promoting Lifestyle Profile II and questions assessing social network satisfaction and employment status.
|
31183915 |
2019 |
Depressive disorder
|
0.330 |
Biomarker
|
disease |
PSYGENET |
ApoE alleles, depression and positive affect in multiple sclerosis.
|
19244396 |
2009 |
Depressive Symptoms
|
0.310 |
Biomarker
|
phenotype |
BEFREE |
The association between executive functioning, coping styles and depressive symptoms in patients with Multiple Sclerosis.
|
31526983 |
2019 |
Depressive Symptoms
|
0.310 |
Biomarker
|
phenotype |
PSYGENET |
To evaluate ApoE alleles in relation to symptoms of depression in a cohort of patients with MS participating in the Sonya Slifka Longitudinal Multiple Sclerosis Study (Slifka Study).
|
19244396 |
2009 |
Encephalomyelitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Herein we demonstrate that two C-type lectin receptors (CLRs), Mcl and Mincle, play an important role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE), an animal model of Multiple Sclerosis (MS).
|
31725411 |
2020 |
Multiple Sclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Herein we demonstrate that two C-type lectin receptors (CLRs), Mcl and Mincle, play an important role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE), an animal model of Multiple Sclerosis (MS).
|
31725411 |
2020 |
Multiple Sclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
During the last 20 years, multiple sclerosis (MS) disease has seen major changes with new diagnostic criteria, a better identification of disease phenotypes, individualization of disease prognosis and the appearance of new therapeutic options in relapsing remitting as well as progressive MS. As a result, the management of MS patients has become more complex and challenging.
|
31816524 |
2020 |
Multiple Sclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Neurologists members of the RIREMS group (Rising Researchers in MS) enrolled MS patients with a TN diagnosis and filled out a spreadsheet comprising their clinical data.
|
31678859 |
2020 |
Multiple Sclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
<b>Background</b>: Multiple sclerosis (MS) is a neurodegenerative disease caused by dysfunction of the immune system that affects the central nervous system (CNS).
|
31588832 |
2020 |
Multiple Sclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
<b>Aims:</b> The aim of this study was to quantify how multiple sclerosis (MS) phenotypes differ from each other in respect of costs and quality-of-life.<b>Materials and methods:</b> The study is based on survey data from Finnish patients with MS (<i>n</i> = 553).
|
31617776 |
2020 |
Encephalomyelitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Here, we unexpectedly found that transfer of feces harvested at peak disease from the experimental autoimmune encephalomyelitis (EAE) model of MS ameliorates disease in recipients in a miRNA-dependent manner.
|
31784260 |
2019 |
Encephalomyelitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Assessment of Mitochondrial Dysfunction in Experimental Autoimmune Encephalomyelitis (EAE) Models of Multiple Sclerosis.
|
31600882 |
2019 |
Encephalomyelitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
The experimental autoimmune encephalomyelitis (EAE) animal model of Multiple Sclerosis (MS) is characterized by episodic neurologic dysfunction arising as a consequence of perivascular mononuclear cell infiltration and demyelination in the CNS.
|
31466733 |
2019 |
Encephalomyelitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Multiple sclerosis (MS) is multifocal, and regional differences in the astrocyte transcriptome occur in experimental autoimmune encephalomyelitis (EAE), an MS model.
|
31040210 |
2019 |
Multiple Sclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Task-oriented training promotes functional recovery in Multiple Sclerosis (MS).
|
31255988 |
2019 |
Multiple Sclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Moreover, class-switched memory B cells were decreased in IFN-β-treated MS compared with HCs (p < 0.001) and untreated MS patients (p = 0.006).
|
31519178 |
2019 |
Multiple Sclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Silymarin Restores Regulatory T Cells (Tregs) Function in Multiple Sclerosis (MS) Patients In Vitro.
|
30806958 |
2019 |
Multiple Sclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Cognitive deficits affect up to 70% of all patients with Multiple Sclerosis (MS) and have a significant impact on quality of life.
|
31760365 |
2019 |
Multiple Sclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
<b>Objective:</b> To test the hypothesis that Multiple Sclerosis (MS) patients have increased peripheral inflammation compared to healthy donors and that this systemic activation of the immune system, reflected by acute phase reactants (APRs) measured in the blood, contributes to intrathecal inflammation, which in turn contributes to the development of disability in MS. <b>Methods:</b> Eight serum APRs measured in a prospectively-collected cross-sectional cohort with a total of 51 healthy donors and 291 untreated MS patients were standardized and assembled into related biomarker clusters to derive global measures of systemic inflammation.
|
31824409 |
2019 |
Multiple Sclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
<b>Introduction:</b> Multiple sclerosis (MS) is an immune-mediated disorder.
|
31790618 |
2019 |
Multiple Sclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
The Italian Neuroimaging Network Initiative (INNI) supports the creation of a repository, where MRI, clinical, and neuropsychological data from multiple sclerosis (MS) patients and healthy controls are collected from Italian Research Centers with internationally recognized expertise in MRI applied to MS.
|
31422457 |
2019 |
Multiple Sclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Of 17 patients, 3 (18%) had MS relapses within 1 year after PML, and 5 (29%) beyond 1 year of PML onset, which is lower than expected in highly active MS patients.
|
31139690 |
2019 |
Multiple Sclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
It established the UK ME/CFS Biobank (UKMEB), which stores data and samples from three groups: participants with ME/CFS, Multiple Sclerosis (MS) and healthy controls.
|
30632248 |
2019 |