MIR376C, microRNA 376c, 442913

N. diseases: 51; N. variants: 0
Disease: Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.060 Biomarker group BEFREE Here, we show that miR-376c, a well-characterized tumor suppressor which inhibits cell proliferation and invasion in osteosarcoma by targeting to transforming growth factor-alpha, suppresses osteoblast proliferation, and differentiation. 29125885 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.060 AlteredExpression group BEFREE High miR-376c-3p expression correlated with poor prognostic features, such as large tumor size and venous infiltration. 30519319 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.060 AlteredExpression group BEFREE Overall, miR-21 and miR-376c expression was higher in tumour compared to healthy tissue samples. 29348831 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.060 Biomarker group BEFREE This study demonstrated that hsa-miR-376c-3p plays an important role in the inhibition of gastric tumor growth and tumor related gene expression both <i>in vitro</i> and <i>in vivo</i>. 27965982 2016
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.060 Biomarker group BEFREE We also show that the edited form of miR-376c-3p is reduced in C vs P samples and in ST tumors compared to LT ones. 26188123 2015
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.060 Biomarker group BEFREE We hypothesized that miR-376c could function as a tumor suppressor in these cells. 23922722 2013