MSH2, mutS homolog 2, 4436

N. diseases: 490; N. variants: 777
Disease: Childhood Brain Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0220603
Disease: Childhood Brain Neoplasm
Childhood Brain Neoplasm 		0.010 GeneticVariation disease BEFREE In Lynch syndrome brain tumors occurred in 14% of the families with significantly higher risks for individuals with MSH2 gene mutations and development of childhood brain tumors in individuals with constitutional MMR defects. 25648859 2015