MSN, moesin, 4478

N. diseases: 140; N. variants: 3
Disease: Neurofibromatosis 2 ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027832
Disease: Neurofibromatosis 2
Neurofibromatosis 2 		0.020 Biomarker disease BEFREE The NF2-encoded protein Merlin is closely related to the Ezrin-Radixin-Moesin family of membrane/cytoskeleton linker proteins, and has been demonstrated to suppress tumor growth by inhibiting extracellular signal-regulated kinase (ERK) and Rac1 activation. 18332868 2008
CUI: C0027832
Disease: Neurofibromatosis 2
Neurofibromatosis 2 		0.020 Biomarker disease BEFREE The gene for NF2, a syndrome typically associated with vestibular schwannomas and meningiomas, is homologous with a family of genes whose members appear to play an important role in bridging the cell membrane with the intracellular cytoskeleton, including moesin, ezrin, radixin, and protein 4.1. 8586465 1995