Cleft upper lip
|
0.700 |
Biomarker
|
disease |
BEFREE |
To evaluate the association of transforming growth factor β3 ( TGFβ3), muscle segment homeobox 1 ( MSX1), Metalloproteinases 3 ( MMP3), and MMP9 genes as candidates for nonsyndromic cleft lip and/or palate in an Indian population.
|
29738289 |
2019 |
Cleft upper lip
|
0.700 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Mutations in the MSX1 gene in Turkish children with non-syndromic tooth agenesis and other dental anomalies.
|
25565750 |
2014 |
Cleft upper lip
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
The patients with non-syndromic cleft lip and/or palate were characterized by similar distribution of MSX1 genotypes and allele in comparison to subjects without oral clefts (P > 0.05).
|
23130753 |
2013 |
Cleft upper lip
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
Conclusion : Our data suggest that CDH1 and MSX1 gene polymorphisms are risk factors for susceptibility to NS-CL/P in a sample of the Iranian population.
|
23231047 |
2013 |
Cleft upper lip
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
Our findings suggest that the nonsense mutation in MSX1 might have resulted in rapid degradation of the mutated transcript and caused the phenotype of tooth agenesis with cleft lip in the Chinese family.
|
22813217 |
2012 |
Cleft upper lip
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
No significant association was found between NSOC and rs3821949 or rs12532 in MSX1 gene, whereas an association was observed between the P147Q variant and cleft lip with cleft palate in the case-control analysis.
|
21689018 |
2011 |
Cleft upper lip
|
0.700 |
GeneticVariation
|
disease |
LHGDN |
MSX1 polymorphism associated with risk of oral cleft in Korea: evidence from case-parent trio and case-control studies.
|
17326252 |
2007 |
Cleft upper lip
|
0.700 |
Biomarker
|
disease |
LHGDN |
[Association study on microsatellite polymorphisms of MSX1 gene and nonsyndromic cleft lip and palate].
|
17557248 |
2007 |
Cleft upper lip
|
0.700 |
GeneticVariation
|
disease |
LHGDN |
Association of MSX1 with nonsyndromic cleft lip and palate in a Colombian population.
|
18177186 |
2007 |
Cleft upper lip
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
MSX1 mutations contribute to nonsyndromic cleft lip in a Thai population.
|
16868654 |
2006 |
Cleft upper lip
|
0.700 |
Biomarker
|
disease |
LHGDN |
Linkage disequilibrium between MSX1 and non-syndromic cleft lip/palate in the Chilean population.
|
15381719 |
2004 |
Cleft upper lip
|
0.700 |
Biomarker
|
disease |
BEFREE |
With likelihood ratio test analysis, "cleft lip only" showed association with MSX1 (p = 0.04) and "cleft palate only" with TGFB3 (p = 0.02).
|
12651933 |
2003 |
Cleft upper lip
|
0.700 |
SusceptibilityMutation
|
disease |
ORPHANET |
MSX1 has been proposed as a gene in which mutations may contribute to non-syndromic forms of cleft lip and/or cleft palate.
|
12807959 |
2003 |
Cleft upper lip
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
MSX1 has been proposed as a gene in which mutations may contribute to non-syndromic forms of cleft lip and/or cleft palate.
|
12807959 |
2003 |
Cleft upper lip
|
0.700 |
Biomarker
|
disease |
BEFREE |
Cleft lip and/or palate with hypodontia outside the cleft region was positively associated with both TGFB3 and MSX1, compared with noncleft controls.
|
12733956 |
2003 |
Cleft upper lip
|
0.700 |
GeneticVariation
|
disease |
LHGDN |
MSX1 has been proposed as a gene in which mutations may contribute to non-syndromic forms of cleft lip and/or cleft palate.
|
12807959 |
2003 |
Cleft upper lip
|
0.700 |
Biomarker
|
disease |
LHGDN |
Cleft lip and/or palate with hypodontia outside the cleft region was positively associated with both TGFB3 and MSX1, compared with noncleft controls.
|
12733956 |
2003 |
Cleft upper lip
|
0.700 |
Biomarker
|
disease |
HPO |
|
|
|