MSX2, msh homeobox 2, 4488

N. diseases: 135; N. variants: 7
Disease: Stomach Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.030 GeneticVariation disease BEFREE Our data indicate that amino acid/nucleotide metabolism-related genes OGDH, PPAT and PCCA acquire somatic mutations in MSH-H GCs and CRCs and that mutational ITH may occur in at least some of these tumors. 27468871 2016
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.030 GeneticVariation disease BEFREE Our data indicate that genes known to be involved in amino acid metabolism recurrently acquire somatic mutations in MSH-H GCs and MSH-H CRCs and that, in addition, mutation ITH does occur in at least some of these tumors. 25450519 2014
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.030 Biomarker disease BEFREE Furthermore, we identified two cancer-specific Hh targets, ELK1 and MSX2, which have an essential role in GC cell growth. 19107131 2009