COX2, cytochrome c oxidase subunit II, 4513

N. diseases: 875; N. variants: 79
Disease: Oestrogen deficiency ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0853662
Disease: Oestrogen deficiency
Oestrogen deficiency 		0.020 Biomarker disease BEFREE However, pretreatment with Melo had no effects on ALT levels and the gene expression levels of TNF-α, IL-6 and HO-1 in either sham or ovx mice, indicating that cox-2 may not participate in increase of CCl<sub>4</sub>-induced ALI caused by estrogen deficiency. 29787990 2018
CUI: C0853662
Disease: Oestrogen deficiency
Oestrogen deficiency 		0.020 AlteredExpression disease BEFREE ALA (100 and 300 mg/kg) intervention to estrogen-deficiency induced bone loss mice (ovariectomized) showed reductions in TRAP+ osteoclasts count, CTX-I expression, levels of IL-1β, IL-2, IL-6, IL10, TNF-α and MCP-1 and iNOS and COX-2. 29061958 2017