|
Congenital heart disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Two Common MTHFR Gene Polymorphisms (C677T and A1298C) and Fetal Congenital Heart Disease Risk: An Updated Meta-Analysis with Trial Sequential Analysis.
|
29554656 |
2018 |
|
Congenital heart disease
|
0.100 |
Biomarker
|
group |
BEFREE |
Risk factors and methylenetetrahydrofolate reductase gene in congenital heart disease.
|
29600076 |
2018 |
|
Congenital heart disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
<b>Background:</b> We performed the present study to better elucidate the correlations of methylenetetrahydrofolate reductase (<i>MTHFR</i>) and methionine synthase reductase (<i>MTRR</i>) gene polymorphisms with the risk of congenital heart diseases (CHD).<b>Methods:</b> Eligible articles were searched in PubMed, Medline, Embase and CNKI.
|
30333252 |
2018 |
|
Congenital heart disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Genetic polymorphism of methylenetetrahydrofolate reductase as a potential risk factor for congenital heart disease: A meta-analysis in Chinese pediatric population.
|
28591039 |
2017 |
|
Congenital heart disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The methylenetetrahydrofolate reductase (MTHFR) gene encoding a critical enzyme, potentially affects susceptibility to some congenital defects like congenital heart disease (CHD).
|
26990189 |
2016 |
|
Congenital heart disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The association of the MTHFR c.1625A>C genetic variant with the risk of congenital heart diseases in the Chinese.
|
25494855 |
2015 |
|
Congenital heart disease
|
0.100 |
Biomarker
|
group |
BEFREE |
Study on Environmental Causes and SNPs of MTHFR, MS and CBS Genes Related to Congenital Heart Disease.
|
26035828 |
2015 |
|
Congenital heart disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The association between c.1333C > T genetic polymorphism of MTHFR gene and the risk of congenital heart diseases.
|
24387084 |
2014 |
|
Congenital heart disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Association analysis between MTHFR genetic polymorphisms and the risk of congenital heart diseases in Chinese Han population.
|
24720776 |
2014 |
|
Congenital heart disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Association between MTHFR polymorphisms and congenital heart disease: a meta-analysis based on 9,329 cases and 15,076 controls.
|
25472587 |
2014 |
|
Congenital heart disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
MTHFR C677T and A1298C gene polymorphisms and their relation to homocysteine level in Egyptian children with congenital heart diseases.
|
23933414 |
2013 |
|
Congenital heart disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Association between the C677T polymorphism of the methylene tetrahydrofolate reductase (MTHFR) gene and congenital heart disease (CHD) is contentious.
|
23876493 |
2013 |
|
Congenital heart disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Methylenetetrahydrofolate reductase gene 677CT polymorphism and isolated congenital heart disease in a Mexican population.
|
22197386 |
2012 |
|
Congenital heart disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Data on the association between the MTHFR C677T polymorphism and congenital heart disease (CHD) are conflicting.
|
21793799 |
2011 |
|
Congenital heart disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Our results suggest that MTHFR polymorphism can be considered a susceptibility gene for this congenital heart disease.
|
19894660 |
2009 |
|
Congenital heart disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The aim of this retrospective case control study was to investigate whether the occurrence of the MTHFR polymorphism is increased in mothers and fathers of children with a congenital heart disease (CHD) in our population.
|
17510921 |
2007 |
|
Congenital heart disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The aim of this study is to investigate whether MTHFR C677T functional genetic variant is associated with an increased risk of congenital heart disease (CHD) development using a family-based case-control design and the Transmission Disequilibrium Test (TDT) approach.
|
16207540 |
2005 |
|
Congenital heart disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Association of the C677T methylenetetrahydrofolate reductase mutation with congenital heart diseases.
|
16305696 |
2005 |
|
Congenital heart disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
However, no data are available so far with respect to the MTHFR 677TT genotype in children with underlying structural congenital heart disease (CHD).
|
11470464 |
2001 |