Atrial Fibrillation
|
0.500 |
GeneticVariation
|
disease |
GWASDB |
Meta-analysis identifies six new susceptibility loci for atrial fibrillation.
|
22544366 |
2012 |
Atrial Fibrillation
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analysis identifies six new susceptibility loci for atrial fibrillation.
|
22544366 |
2012 |
Atrial Fibrillation
|
0.500 |
Biomarker
|
disease |
CTD_human |
Meta-analysis identifies six new susceptibility loci for atrial fibrillation.
|
22544366 |
2012 |
Atrial Fibrillation
|
0.500 |
Biomarker
|
disease |
BEFREE |
Recent genome-wide association studies have identified 3 loci, on chromosomes 4q25 (near PITX2), 16q22 (in ZFHX3), and 1q21 (in KCNN3), that associate with either typical or lone AF.
|
22726630 |
2012 |
Atrial Fibrillation
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Each of these underlying pathologies may have a specific genetic architecture.Previous genome-wide association studies (GWAS) showed association of variants near PITX2 and ZFHX3 with atrial fibrillation and stroke.
|
22776031 |
2012 |
Atrial Fibrillation
|
0.500 |
Biomarker
|
disease |
BEFREE |
The study expands the association between ZFHX3 and AF to a non-European ancestry population and provides the first evidence of a cross-race susceptibility of the 16q22 AF locus.
|
21107608 |
2011 |
Atrial Fibrillation
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analyses of 896 prevalent (15,768 referents) and 2,517 incident (21,337 referents) AF cases identified a new locus for AF (ZFHX3, rs2106261, risk ratio RR = 1.19; P = 2.3 x 10(-7)).
|
19597492 |
2009 |
Atrial Fibrillation
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Meta-analyses of 896 prevalent (15,768 referents) and 2,517 incident (21,337 referents) AF cases identified a new locus for AF (ZFHX3, rs2106261, risk ratio RR = 1.19; P = 2.3 x 10(-7)).
|
19597492 |
2009 |
Atrial Fibrillation
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
A variant in the ZFHX3 gene on chromosome 16q22, rs7193343-T, associated significantly with AF (odds ratio OR = 1.21, P = 1.4 x 10(-10)).
|
19597491 |
2009 |
Atrial Fibrillation
|
0.500 |
GeneticVariation
|
disease |
GWASDB |
A variant in the ZFHX3 gene on chromosome 16q22, rs7193343-T, associated significantly with AF (odds ratio OR = 1.21, P = 1.4 x 10(-10)).
|
19597491 |
2009 |
Atrial Fibrillation
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
A variant in the ZFHX3 gene on chromosome 16q22, rs7193343-T, associated significantly with AF (odds ratio OR = 1.21, P = 1.4 x 10(-10)).
|
19597491 |
2009 |
Atrial Fibrillation
|
0.500 |
Biomarker
|
disease |
CTD_human |
A variant in the ZFHX3 gene on chromosome 16q22, rs7193343-T, associated significantly with AF (odds ratio OR = 1.21, P = 1.4 x 10(-10)).
|
19597491 |
2009 |
Atrial Fibrillation
|
0.500 |
Biomarker
|
disease |
CTD_human |
Meta-analyses of 896 prevalent (15,768 referents) and 2,517 incident (21,337 referents) AF cases identified a new locus for AF (ZFHX3, rs2106261, risk ratio RR = 1.19; P = 2.3 x 10(-7)).
|
19597492 |
2009 |
Atrial Fibrillation
|
0.500 |
GeneticVariation
|
disease |
GWASDB |
Meta-analyses of 896 prevalent (15,768 referents) and 2,517 incident (21,337 referents) AF cases identified a new locus for AF (ZFHX3, rs2106261, risk ratio RR = 1.19; P = 2.3 x 10(-7)).
|
19597492 |
2009 |