ZFHX3, zinc finger homeobox 3, 463

N. diseases: 85; N. variants: 39
Disease: Atrial Fibrillation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.500 GeneticVariation disease GWASCAT Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. 27790247 2016
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.500 GeneticVariation disease GWASCAT Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. 28416818 2017
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.500 Biomarker disease BEFREE This study suggests a contribution of ZFHX3 to AF remodeling and response to therapy. 28381281 2017
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.500 GeneticVariation disease GWASCAT Korean atrial fibrillation network genome-wide association study for early-onset atrial fibrillation identifies novel susceptibility loci. 28460022 2017
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.500 GeneticVariation disease GWASCAT Identification of six new genetic loci associated with atrial fibrillation in the Japanese population. 28416822 2017
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.500 GeneticVariation disease BEFREE We showed that the ZFHX3 polymorphism, rs2106261 (A allele), was a risk marker for AF and AF-related phenotypes. 28007413 2017
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.500 Biomarker disease CTD_human Biobank-driven genomic discovery yields new insight into atrial fibrillation biology. 30061737 2018
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.500 GeneticVariation disease GWASCAT Biobank-driven genomic discovery yields new insight into atrial fibrillation biology. 30061737 2018
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.500 GeneticVariation disease BEFREE The ZFHX3 SNP rs2106261 minor allele is associated with lower AF recurrence rate after pulmonary vein isolation. 30180182 2018
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.500 GeneticVariation disease GWASCAT Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development. 29290336 2018
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.500 GeneticVariation disease GWASCAT Multi-ethnic genome-wide association study for atrial fibrillation. 29892015 2018
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.500 Biomarker disease CTD_human Multi-ethnic genome-wide association study for atrial fibrillation. 29892015 2018
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.500 GeneticVariation disease BEFREE Loss-of-function mutation in the zinc finger homeobox 3 gene (ZFHX3) is associated with increased risk of AF. 31152485 2019
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.500 GeneticVariation disease BEFREE Rs13376333 on chromosome 1q21 (in KCNN3), rs7193343 and rs2106261 on chromosome 16q22 (in ZFHX3) were not associated with AF recurrence in our meta-analysis. 31169720 2019