ZFHX3, zinc finger homeobox 3, 463

N. diseases: 85; N. variants: 39
Disease: Ischemic stroke ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.130 GeneticVariation disease BEFREE There was no association between clinical severity and recurrence with variants rs2383207 (CDKN2B-AS1) for atherothrombotic IS and variants rs879324 (ZFHX3), rs966221 (PDE4D), and rs152312 (PDE4D) for cardioembolic IS. 31757599 2020
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.130 GeneticVariation disease GWASCAT Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. 26708676 2016
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.130 GeneticVariation disease BEFREE Nonparametric linkage analysis revealed that the rs1800796 polymorphism in the interleukin-6 (IL-6) gene is significantly linked to the small arterial occlusion (SAO) subtype (p=0.022), while the rs7193343 polymorphism in the ZFHX3 gene is linked to IS (p=0.002) under the dominant model. 25325233 2014
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.130 GeneticVariation disease BEFREE A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke. 19597491 2009