MYO7A, myosin VIIA, 4647

N. diseases: 104; N. variants: 194
Disease: Blindness, Legal ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0271215
Disease: Blindness, Legal
Blindness, Legal 		0.010 GeneticVariation disease BEFREE Longitudinal analysis showed that visual acuity and visual field decreased more rapidly in subjects carrying MYO7A mutations than in those carrying USH2A mutations (mean annual exponential rates of decline of 3.92 vs. 3.44% and of 8.52 vs. 4.97%, respectively), and the former patients reached legal blindness on average 15 years earlier than the latter. 27828912 2017