MYOD1, myogenic differentiation 1, 4654

N. diseases: 106; N. variants: 2
Disease: Colorectal Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.040 GeneticVariation disease BEFREE The rest changed greatly in the methylation pattern in colorectal cancer (CRC): cyclin A1 (cyclin a1) (100%, 65/65), caudal type homeobox transcription factor 1 (CDX1) (100%, 65/65), RAR- (85%, 55/65), myogenic factor 3 (MYOD1) (69%, 45/65), cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) (p15(INK4b)) (68%, 44/65), prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (COX2) (72%, 47/65), cadherin 13, H-cadherin (heart) (CDH13) (65%, 42/65), CAAX box 1 (CXX1) (58%, 38/65), tumor protein p73 (p73) (63%, 41/65) and Wilms tumor 1 (WT1) (58%, 38/65). 15526363 2004
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.040 PosttranslationalModification disease BEFREE These results suggest that MYOD1 hypermethylation plays an important role in colorectal cancer and may be a novel prognostic factor. 14767572 2004
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.040 PosttranslationalModification disease BEFREE Further work is required to determine whether the hypermethylation of Myf-3 observed in colorectal cancers is a specific alteration with functional significance or whether it reflects non-specific methylation imbalances occurring early during tumorigenesis. 10096240 1999
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.040 PosttranslationalModification disease BEFREE Hypermethylation of the Myf-3 gene in human colorectal cancer. 9066689 1997