ATF3, activating transcription factor 3, 467

N. diseases: 228; N. variants: 4
Disease: Kidney Failure, Acute ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.030 Biomarker disease BEFREE Together, our studies reveal a novel regulatory mechanism of MCP-1 expression mediated by the exosomal ATF3 RNA under renal I/R insult and suggest a potential targeted therapy for I/R induced acute kidney injury. 24420912 2014
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.030 Biomarker disease BEFREE A recent clinical study also reported that ATF3 can serve as an indicator of acute kidney injury (AKI). 21495874 2011
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.030 Biomarker disease BEFREE Our findings suggest that transcription factor ATF3 may provide a novel renal tubular cell biomarker for acute kidney injury while WT-1 may detect early podocyte injury. 18509321 2008