ATF4, activating transcription factor 4, 468

N. diseases: 178; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0242184
Disease: Hypoxia
Hypoxia
0.300 Biomarker phenotype CTD_human Here we report a differential response of cancer cells to hypoxia and anoxia by demonstrating the induction of activating transcription factor-4 (ATF-4) and growth arrest DNA damage 153 (GADD153) protein specifically in anoxia and the lack of induction in hypoxia. 14604972 2004