NBN, nibrin, 4683

N. diseases: 291; N. variants: 194
Disease: Malignant neoplasm of pancreas ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.020 GeneticVariation disease BEFREE The c.657del5 variant in the NBN gene predisposes to pancreatic cancer. 27150568 2016
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.020 GeneticVariation disease BEFREE The founder mutation in NBS1 (657del5) was associated with an increased risk of PaCa in heterozygous carriers, indicating that this mutation appears to predispose to cancer of the pancreas. 27038244 2016