NCL, nucleolin, 4691

N. diseases: 167; N. variants: 4
Disease: tumor vasculature ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1658953
Disease: tumor vasculature
tumor vasculature 		0.030 Biomarker phenotype BEFREE One of the strategies to overcome this problem is targeting the more accessible tumor vasculature via molecules such as nucleolin, which is expressed at the surface of cancer and angiogenic endothelial cells, thus enabling a dual cellular targeting strategy. 31271738 2019
CUI: C1658953
Disease: tumor vasculature
tumor vasculature 		0.030 Biomarker phenotype BEFREE With selective targeting of nucleolin on both tumor vasculature and tumor cells, this intrinsically radioactive nMOF can find broad application in cancer theranostics. 28345871 2017
CUI: C1658953
Disease: tumor vasculature
tumor vasculature 		0.030 Biomarker phenotype BEFREE Cell surface nucleolin antagonist causes endothelial cell apoptosis and normalization of tumor vasculature. 19225898 2009