NDN, necdin, MAGE family member, 4692

N. diseases: 124; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.020 AlteredExpression disease BEFREE Forced expression of necdin enhances mitochondrial function in primary cortical neurons and human SH-SY5Y neuroblastoma cells to prevent mitochondrial respiratory chain inhibitor-induced degeneration. 26971449 2016
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.020 Biomarker disease BEFREE The present studies demonstrate that the effects of necdin on the susceptibility of neuroblastoma cells to oxidant stress are dependent on the ratio of p75NTR to TrkA in the cell. 21150695 2011