ATM, ATM serine/threonine kinase, 472

N. diseases: 684; N. variants: 974
Disease: Adenoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001430
Disease: Adenoma
Adenoma 		0.040 AlteredExpression group BEFREE In particular, MLH1, ATM and FHIT gene promoters were found to be significantly hypermethylated in recurring adenomas. 25091577 2014
CUI: C0001430
Disease: Adenoma
Adenoma 		0.040 GeneticVariation group BEFREE Among the top findings, an SNP (rs17503908) in ataxia telangiectasia mutated (ATM) was inversely related to adenoma risk (OR = 0.75, 95% CI = 0.63-0.91). 21504893 2011
CUI: C0001430
Disease: Adenoma
Adenoma 		0.040 GeneticVariation group BEFREE We conclude that activating mutations of the AT1 receptor are not a major cause of the development of adrenal adenomas, if at all. 9330590 1997
CUI: C0001430
Disease: Adenoma
Adenoma 		0.040 GeneticVariation group BEFREE In patients with aldosterone-producing adenomas either responsive or unresponsive to the renin-angiotensin system, no differences were detected using SSCP analysis in the coding region of the AT1 receptor gene in peripheral blood or tumour tissue. 8582102 1996