ATM, ATM serine/threonine kinase, 472

N. diseases: 684; N. variants: 974
Disease: Tumor Initiation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0598935
Disease: Tumor Initiation
Tumor Initiation 		0.020 Biomarker phenotype BEFREE Whether ATM deficiency impacts on tumor initiation or also on the maintenance of the malignant state is unclear. 31690822 2020
CUI: C0598935
Disease: Tumor Initiation
Tumor Initiation 		0.020 Biomarker phenotype BEFREE These observations, along with reports that identify ATM loss of function as an event that may promote tumor initiation and progression, point to ATM as a bona fide tumor suppressor. 24681585 2014