NEFL, neurofilament light, 4747

N. diseases: 247; N. variants: 26
Disease: Mental disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004936
Disease: Mental disorders
Mental disorders 		0.030 Biomarker group BEFREE Neurofilament light distinguished neurodegenerative or neurological disorder from psychiatric disorder with an area under the curve of 0.94 (95% confidence intervals = [0.89, 0.98]); a cut-off of 1332 pg/mL was associated with 87% sensitivity and 90% specificity. 31220922 2020
CUI: C0004936
Disease: Mental disorders
Mental disorders 		0.030 Biomarker group BEFREE Serum neurofilament light chain is a discriminative biomarker between frontotemporal lobar degeneration and primary psychiatric disorders. 31595378 2020
CUI: C0004936
Disease: Mental disorders
Mental disorders 		0.030 AlteredExpression group BEFREE Neurofilaments are cytoskeletal proteins in the neurons, and several studies have reported elevated levels of neurofilament light chain (NfL) in cerebrospinal fluid of neurodegenerative as well as psychiatric disorders. 30953863 2019