NEFL, neurofilament light, 4747

N. diseases: 247; N. variants: 26
Disease: Spinal Muscular Atrophy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026847
Disease: Spinal Muscular Atrophy
Spinal Muscular Atrophy 		0.030 Biomarker disease BEFREE Neurofilament light chain in serum of adolescent and adult SMA patients under treatment with nusinersen. 31552549 2020
CUI: C0026847
Disease: Spinal Muscular Atrophy
Spinal Muscular Atrophy 		0.030 Biomarker disease BEFREE NfL, protein and quotients of albumin (Q<sub>alb</sub>) increased slightly in SMA patients after the fourth injection. 31205491 2019
CUI: C0026847
Disease: Spinal Muscular Atrophy
Spinal Muscular Atrophy 		0.030 AlteredExpression disease BEFREE Baseline levels of NFL (4598 ± 981 vs 148 ± 39, P = 0.001), tau (939 ± 159 vs 404 ± 86, P = 0.02), and GFAP (236 ± 44 vs 108 ± 26, P = 0.02) were significantly higher in SMA children than controls. 31123861 2019