NEFL, neurofilament light, 4747

N. diseases: 247; N. variants: 26
Disease: Motor neuron atrophy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4024896
Disease: Motor neuron atrophy
Motor neuron atrophy 		0.020 AlteredExpression disease BEFREE Serum neurofilament light chain levels as a marker of upper motor neuron degeneration in patients with Amyotrophic Lateral Sclerosis. 29908069 2019
CUI: C4024896
Disease: Motor neuron atrophy
Motor neuron atrophy 		0.020 AlteredExpression disease BEFREE Reexamination of motor neuron degeneration due to alterations of neurofilament (NF) expression suggests that disruption of assembly with aggregation of the light neurofilament (NFL) protein may be an upstream event and contributing factor leading to the preferential degeneration of motor neurons. 17006927 2006