NFE2L2, nuclear factor, erythroid 2 like 2, 4780

N. diseases: 89; N. variants: 14
Disease: Diabetic Nephropathy ×
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.600 Therapeutic disease CTD_human Mechanistic studies in both in vivo and in vitro systems showed that the Nrf2-mediated protection against diabetic nephropathy is, at least, partially through inhibition of transforming growth factor-beta1 (TGF-beta1) and reduction of extracellular matrix production. 20103708 2010