|
Congenital Abnormality
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a common birth defect with a complex genetic architecture.
|
30273098 |
2019 |
|
Congenital Abnormality
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common congenital anomalies, with a complex and still not fully understood etiology.
|
22887353 |
2012 |
|
Congenital Abnormality
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common birth defects and has a multifactorial etiology that includes both genetic and environmental components.
|
19320731 |
2009 |
|
Congenital Abnormality
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Nonsyndromic cleft lip with or without cleft palate (NSCL ± P) is the most common orofacial birth defect, exhibiting variable prevalence around the world, often attributed to ethnic and environmental differences.
|
26198054 |
2015 |
|
Congenital Abnormality
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The isolated type of orofacial cleft, termed non-syndromic cleft lip with or without cleft palate (NSCL/P), is the second most common birth defect in China, with Asians having the highest incidence in the world.
|
30578914 |
2018 |
|
Congenital Abnormality
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Non-syndromic cleft lip with or without cleft palate (NSCL/P) are the most common human congenital birth defects with a complex etiology.
|
30024657 |
2018 |
|
Congenital Abnormality
|
0.100 |
GeneticVariation
|
group |
BEFREE |
To understand the genetic basis of nonsyndromic cleft lip with or without cleft palate (NSCL/P) susceptibility, a complex and highly prevalent congenital malformation, we searched for genetic variants with a regulatory role in a disease-related tissue, the lip muscle (orbicularis oris muscle [OOM]), of affected individuals.
|
29053389 |
2018 |
|
Congenital Abnormality
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Our study provided additional understanding of the genetic etiology of NSCL/P and underlined the importance of considering gene-gene interaction in the etiology of this common craniofacial malformation.
|
29341488 |
2018 |
|
Congenital Abnormality
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common congenital malformations and a susceptibility locus on chromosome 8q24 has been replicated as a genetic risk factor for NSCL/P in patients of European and Asian descent.
|
22044123 |
2012 |
|
Congenital Abnormality
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is the most common craniofacial malformation, with an incidence of about 1/700 live births, although variable according to ethnicity.
|
24942095 |
2014 |
|
Congenital Abnormality
|
0.100 |
GeneticVariation
|
group |
BEFREE |
In combination with results from our previous study using the same sample, our data suggest that the majority of the known NSCL/P susceptibility regions identified to date also confer risk for this malformation in the Mesoamerican population.
|
24382704 |
2014 |
|
Congenital Abnormality
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is the most common orofacial birth defect with a wide range prevalence among different populations.
|
23679094 |
2013 |
|
Congenital Abnormality
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is a common structural malformation with a complex and multifactorial aetiology.
|
24606907 |
2014 |
|
Congenital Abnormality
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common birth defects and has a multifactorial etiology that includes both genetic and environmental factors.
|
20572868 |
2010 |
|
Congenital defects
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Non-syndromic cleft lip with or without cleft palate (NSCL/P) are the most common human congenital birth defects with a complex etiology.
|
30024657 |
2018 |
|
Congenital defects
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common birth defects and has a multifactorial etiology that includes both genetic and environmental components.
|
19320731 |
2009 |
|
Congenital defects
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common birth defects and has a multifactorial etiology that includes both genetic and environmental factors.
|
20572868 |
2010 |
|
Dysmorphism
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a common birth defect with a complex genetic architecture.
|
30273098 |
2019 |
|
Dysmorphism
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Nonsyndromic cleft lip with or without cleft palate (NSCL ± P) is the most common orofacial birth defect, exhibiting variable prevalence around the world, often attributed to ethnic and environmental differences.
|
26198054 |
2015 |
|
Dysmorphism
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The isolated type of orofacial cleft, termed non-syndromic cleft lip with or without cleft palate (NSCL/P), is the second most common birth defect in China, with Asians having the highest incidence in the world.
|
30578914 |
2018 |
|
Dysmorphism
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is the most common orofacial birth defect with a wide range prevalence among different populations.
|
23679094 |
2013 |
|
Deformity
|
0.070 |
GeneticVariation
|
group |
BEFREE |
Our study provided additional understanding of the genetic etiology of NSCL/P and underlined the importance of considering gene-gene interaction in the etiology of this common craniofacial malformation.
|
29341488 |
2018 |
|
Deformity
|
0.070 |
GeneticVariation
|
group |
BEFREE |
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is the most common craniofacial malformation, with an incidence of about 1/700 live births, although variable according to ethnicity.
|
24942095 |
2014 |
|
Deformity
|
0.070 |
GeneticVariation
|
group |
BEFREE |
In combination with results from our previous study using the same sample, our data suggest that the majority of the known NSCL/P susceptibility regions identified to date also confer risk for this malformation in the Mesoamerican population.
|
24382704 |
2014 |
|
Deformity
|
0.070 |
GeneticVariation
|
group |
BEFREE |
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is a common structural malformation with a complex and multifactorial aetiology.
|
24606907 |
2014 |