Neuroblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
HEN1 and HEN2 are coexpressed in the IMR-32 human neuroblastoma cell line, and they encode highly related proteins of 133 and 135 residues, respectively, that share 98% amino acid identity in their hHLH domains.
|
1528853 |
1992 |
Central neuroblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
HEN1 and HEN2 are coexpressed in the IMR-32 human neuroblastoma cell line, and they encode highly related proteins of 133 and 135 residues, respectively, that share 98% amino acid identity in their hHLH domains.
|
1528853 |
1992 |
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
The HEN1 gene was identified on the basis of cross-hybridization with TAL1, a known bHLH gene implicated in T-cell acute lymphoblastic leukemia.
|
1528853 |
1992 |
Childhood Neuroblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
HEN1 and HEN2 are coexpressed in the IMR-32 human neuroblastoma cell line, and they encode highly related proteins of 133 and 135 residues, respectively, that share 98% amino acid identity in their hHLH domains.
|
1528853 |
1992 |
Non-Small Cell Lung Carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Binding sites for epidermal growth factor (EGF) had been described previously in NSCL, therefore we found erbB homologue transcripts coding for the EGF receptor in all NSCLC cell lines.
|
1690210 |
1990 |
Carcinogenesis
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
These findings suggest that deregulated expression of p16 is involved in the multistage process of NSCL carcinogenesis and that deletions may represent a predominant mechanism of p16INK4A inactivation.
|
10470133 |
1999 |
Adenocarcinoma
|
0.010 |
GeneticVariation
|
group |
BEFREE |
We investigated 33 cases of NSCL for LOH at 5q21: 22 squamous cell and 11 adenocarcinomas.
|
10549031 |
1999 |
Van der Woude syndrome
|
0.020 |
Biomarker
|
disease |
BEFREE |
No evidence for linkage of NSCL/P to vWS was found on the 21 families using the LOD score approach.
|
11746036 |
2001 |
Neoplasm Metastasis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
In conclusion, although MMP9 may potentially promote tumor growth and metastasis, production of MMP-dependent anti-angiogenic factors seems to override these effects and protects the host from NSCL growth and progression.
|
16086239 |
2005 |
Hypodontia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to characterize Swedish families with non-syndromic cleft lip and/or palate (NSCL/P) for mutations or other sequence variants in the interferon regulatory factor 6 (IRF6) gene, as well as to describe their cleft phenotypes and hypodontia.
|
18209213 |
2008 |
Medulloblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma.
|
18231642 |
2008 |
Childhood Medulloblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma.
|
18231642 |
2008 |
Adult Medulloblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma.
|
18231642 |
2008 |
Congenital Abnormality
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common birth defects and has a multifactorial etiology that includes both genetic and environmental components.
|
19320731 |
2009 |
Congenital defects
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common birth defects and has a multifactorial etiology that includes both genetic and environmental components.
|
19320731 |
2009 |
Cleft Palate
|
0.050 |
Biomarker
|
disease |
BEFREE |
Nonsyndromic cases of cleft lip with or without cleft palate (NSCL/P) and cleft palate only (NSCPO) are considered to have a multifactorial etiology which involves both genetic and environmental factors.
|
19938073 |
2009 |
Cleft palate, isolated
|
0.050 |
Biomarker
|
disease |
BEFREE |
Nonsyndromic cases of cleft lip with or without cleft palate (NSCL/P) and cleft palate only (NSCPO) are considered to have a multifactorial etiology which involves both genetic and environmental factors.
|
19938073 |
2009 |
Uranostaphyloschisis
|
0.050 |
Biomarker
|
disease |
BEFREE |
Nonsyndromic cases of cleft lip with or without cleft palate (NSCL/P) and cleft palate only (NSCPO) are considered to have a multifactorial etiology which involves both genetic and environmental factors.
|
19938073 |
2009 |
Cleft Palate
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
The purpose of this study is to follow the familial incidence of non-syndromic or isolated cleft lip, with or without cleft palate (NSCL/P), and to analyze the relationships between the type of NSCL/P in the affected individual and his/her parent, looking at children in the first grade.
|
20526256 |
2010 |
Cleft palate, isolated
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
The purpose of this study is to follow the familial incidence of non-syndromic or isolated cleft lip, with or without cleft palate (NSCL/P), and to analyze the relationships between the type of NSCL/P in the affected individual and his/her parent, looking at children in the first grade.
|
20526256 |
2010 |
Uranostaphyloschisis
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
The purpose of this study is to follow the familial incidence of non-syndromic or isolated cleft lip, with or without cleft palate (NSCL/P), and to analyze the relationships between the type of NSCL/P in the affected individual and his/her parent, looking at children in the first grade.
|
20526256 |
2010 |
Congenital Abnormality
|
0.100 |
Biomarker
|
group |
BEFREE |
Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common of all birth defects.
|
20564431 |
2010 |
Congenital defects
|
0.100 |
Biomarker
|
group |
BEFREE |
Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common of all birth defects.
|
20564431 |
2010 |
Congenital Abnormality
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common birth defects and has a multifactorial etiology that includes both genetic and environmental factors.
|
20572868 |
2010 |
Congenital defects
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common birth defects and has a multifactorial etiology that includes both genetic and environmental factors.
|
20572868 |
2010 |