Disease: Malignant neoplasm of colon and/or rectum ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 Biomarker disease BEFREE Overexpression of NDP kinase nm23 associated with ploidy image analysis in colorectal cancer. 8572601 1996
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 AlteredExpression disease BEFREE Immunohistochemical studies of the nm23-H1 protein expression are of minor value in the staging and prognostic prediction of colorectal cancer. 8912537 1996
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 Biomarker disease BEFREE The association of death from colorectal cancer and nm23 status reached marginal significance in this study (P = 0.0417). 8195929 1994
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 GeneticVariation disease BEFREE This finding suggests that NM23-H1 mutations are rare events in human colorectal cancer. 8297127 1994
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 AlteredExpression disease BEFREE In order to investigate its role in the progression of colorectal cancer, we analysed 22 liver metastases of this malignancy with respect to mutational changes, loss of heterozygosity and expression levels of nm23-H1. 7981087 1994
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 AlteredExpression disease BEFREE High level of Nm23-H1 gene expression is associated with local colorectal cancer progression not with metastases. 7947079 1994
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 Biomarker disease BEFREE These observations indicate that the nm23 gene may play a role in the suppression of liver metastasis of colorectal cancer. 8217591 1993
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 GeneticVariation disease BEFREE Mutation in the nm23 gene is associated with metastasis in colorectal cancer. 7916650 1993
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.090 GeneticVariation disease BEFREE A prospective study analysed the prognostic value of nm23-H1 allelic deletions in colorectal cancer. 1679868 1991